Kate Makrigiannis
I build and ship products,
lead strong teams,
and make delivery predictable
14 years turning ambiguity into outcomes across healthcare, defense, and enterprise, now shipping working software in days, not months, with AI. Open to full-time product leadership roles, and available for fractional and sprint engagements.
Where I've worked
Deep experience across four domains.
Healthcare
FLUXX, Sperity,
Kaiser Permanente
Regulated product delivery in clinical, wellness, and health education environments
View workDefense
U.S. Space Force, Kessel Run, USAF
Modern software practices inside government organizations with high-security requirements
View workEnterprise
Goldman Sachs, Zendesk, Home Depot
Platform products at scale, from internal tooling to customer-facing systems
View workAI & Product
Artium, Agentic Skill Workflows & OpenAI Certifications
AI-assisted workflows, agent systems, and integrating ML into product strategy
Browse skillsProduct case studies
Outcomes across healthcare, defense, and enterprise.
Launching FLUXX: An AI-Powered Menopause Platform
Director of Product (Fractional)
MVP live in under 6 months. 47% engagement and 800+ quiz completions, above typical early-healthtech benchmarks, driven by intent-based re-engagement rather than guilt-driven notifications. 38% drop in quiz abandonment. Organic search nearly tripled month over month. AI recommendations pre-screened by a simulated clinician panel, then validated by real clinicians.
Designing a Wellness MVP for Biomarker-Driven Preventative Care
Director of Product (Fractional)
Took the product from a Wix site to a functioning, HIPAA-compliant MVP validated with an 18-member first cohort. The Sperity Score gave members a single daily metric instead of a data dump. Built 5 member personas, service blueprints, and onboarding journey maps, and left behind delivery rituals the team runs without a fractional leader.
Delivery Transformation: Reduced Cycle Times
Principal Product Coach
One portfolio cut 12 weeks of delivery cycle time, traced directly to blockers value stream mapping surfaced. Coached 70+ teams across 9 portfolios. Aligned 300+ product org members on roadmaps, roles, and rituals. Rated 'Excellent' by leadership and called 'a visionary and a person of action.'
U.S. Space Force - Platform Delivery Modernization
Product Portfolio Lead
MVP cycle time fell from 6 months to 2 weeks, a 92% reduction, because the OA bottleneck was broken once for everyone rather than worked around team by team. First app reached production. Trust restored across engineering, security, and leadership.
Go deeper
Explore what I've built, how I work, and what I share.
Built for fun
Fantasy leagues real people play.
Each one runs a full season on its own domain: a snake draft, a scoring engine that settles arguments, weekly recaps, and an archive once the finale airs. They are small products with real users and a deadline that does not move, which makes them the most honest practice I get.
Survivor Fantasy
Fantasy league for CBS Survivor. Draft castaways, score tribal councils, and compete with your tribe all season.
BBFantasy
Big Brother fantasy league. Draft the house, make your weekly picks, and compete with your friends all season.
PlayTraitorsFantasy
The Traitors fantasy league. Draft the castle, score every banishment and murder, and settle who read the season right.
Let's talk about what
you're building
Open to full-time product leadership roles, and available for fractional and sprint engagements. If you're building something ambitious, I'd love to hear about it.
Get in touch