Kate Makrigiannis
I build great products,
lead strong teams,
and make delivery predictable
14 years turning ambiguity into outcomes across healthcare, defense, and enterprise. Currently exploring product leadership roles.
Where I've worked
Deep experience across four domains.
Healthcare
FLUXX, Sperity,
Kaiser Permanente
Regulated product delivery in clinical, wellness, and health education environments
Defense
U.S. Space Force, Kessel Run, USAF
Modern software practices inside government organizations with high-security requirements
Enterprise
Goldman Sachs, Zendesk, Home Depot
Platform products at scale, from internal tooling to customer-facing systems
AI & Product
Artium, Skillet, 580+ skills
AI-assisted workflows, agent systems, and integrating ML into product strategy
Product case studies
Outcomes across healthcare, defense, and enterprise.
Launching FLUXX: An AI-Powered Menopause Platform
Director of Product (Fractional)
MVP live in under 6 months. 120 active users, 47% engagement rate, 800+ quiz completions, 38% reduction in quiz abandonment. Built a 20-member Clinician Advisory Board and validated AI recommendations against real clinical panels.
Designing a Wellness MVP for Biomarker-Driven Preventative Care
Director of Product (Fractional)
Took the product from vaporware to a functioning, HIPAA-compliant MVP with 18 early users. Built 5 member personas, service blueprints, and onboarding journey maps. Established repeatable delivery rituals that replaced founder-driven decisions.
Delivery Transformation: Reduced Cycle Times
Principal Product Coach
One portfolio cut delivery cycle time by 12 weeks via value stream mapping. Coached 70+ teams across 9 portfolios. Empowered 300+ product org members to align roadmaps, roles, and rituals. Rated 'Excellent' by leadership - called 'a visionary and a person of action.'
U.S. Space Force - Platform Delivery Modernization
Product Portfolio Lead
Reduced MVP cycle time from 6 months to 2 weeks (92% faster delivery). Cleared Operational Acceptance bottleneck for the first app to reach production. Restored trust across engineering, security, and leadership.
Go deeper
Explore what I've built, how I work, and what I share.
Let's talk about what
you're building
Currently exploring product leadership roles. If you're building something ambitious, I'd love to hear about it.
Get in touch